Susceptibility of congenitally athymic (nude) mice to sporotrichosis

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Susceptibility of congenitally athymic (nude) mice to sporotrichosis.

Congenitally athymic (nu/nu) mice were found to be more susceptible to intravenous challenge with Sporothrix schenckii than their phenotypically normal (nu/+) littermates as measured by lethality and the number of viable yeast cells in the liver 7 days postinfection. Thymus reconstitution of nu/nu mice (nu/thy) conferred a significant degree of resistance to sporotrichosis. Immunization greatly...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1983

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.40.1.417-420.1983